Vellore Institute of Technology | India
Nilmadhab Roy is an emerging researcher in the field of bioinorganic and medicinal chemistry, recognized for his innovative work on metal-based therapeutic agents. He obtained his Master of Science (M.Sc.) in Physical Chemistry from Vidyasagar University in 2014 and successfully qualified for the prestigious All-India GATE examination in 2015. Pursuing his passion for interdisciplinary research, he began his Ph.D. at VIT, Vellore, under the supervision of Dr. Priyankar Paira, MRSC, where he explored the design and synthesis of mitochondria-targeting Ru(II), Ir(III), and Re(I)-based half-sandwich and cyclometallated complexes for chemodynamic therapy. His research bridges coordination chemistry, photochemistry, and cancer therapeutics, focusing on developing metal complexes that selectively target cellular organelles to induce oxidative stress and apoptosis in cancer cells. Through his work, Roy contributes significantly to understanding how transition-metal coordination frameworks can be engineered for bioactive and diagnostic applications. With over 30 publications in high-impact journals such as those of the American Chemical Society (ACS), the Royal Society of Chemistry (RSC), and Elsevier, his contributions demonstrate strong scientific rigor and creativity. His findings provide valuable insights into structure-activity relationships and potential therapeutic mechanisms, advancing the frontier of chemodynamic and photodynamic cancer therapy. Currently, he is an active member of the Society of Biological Inorganic Chemistry (SBIC), reflecting his ongoing engagement with the international scientific community. Nilmadhab Roy’s work represents a forward-thinking approach to integrating chemical innovation with biomedical application.
Profiles: Scopus | Orcid | Google Scholar
Featured Publications
-
Kar, B., Das, U., Roy, N., & Paira, P. (2023). Recent advances on organelle specific Ru(II)/Ir(III)/Re(I) based complexes for photodynamic therapy. Coordination Chemistry Reviews, 474, 214860.
-
Sharma, A., Sudhindra, P., Roy, N., & Paira, P. (2020). Advances in novel iridium (III) based complexes for anticancer applications: A review. Inorganica Chimica Acta, 513, 119925.
-
Pete, S., Roy, N., Kar, B., & Paira, P. (2022). Construction of homo and heteronuclear Ru(II), Ir(III) and Re(I) complexes for target specific cancer therapy. Coordination Chemistry Reviews, 460, 214462.
-
Sarkar, B., Mondal, A., Madaan, Y., Roy, N., Moorthy, A., Kuo, Y. C., & Paira, P. (2019). Luminescent anticancer ruthenium(II)-p-cymene complexes of extended imidazophenanthroline ligands: Synthesis, structure, reactivity, biomolecular interactions and live cell studies. Dalton Transactions, 48(32), 12257–12271.
-
Sudhindra, P., Sharma, S. A., Roy, N., Moharana, P., & Paira, P. (2020). Recent advances in cytotoxicity, cellular uptake and mechanism of action of ruthenium metallodrugs: A review. Polyhedron, 192, 114827.