Jing Li | Cardiovascular Disease | Best Researcher Award

Prof. Jing Li | Cardiovascular Disease | Best Researcher Award

πŸ‘€Β Prof. Jing Li, beijing chaoyang hospital, China

Dr. Jing Li, PhD, is an Associate Professor at the Heart Center & Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. A distinguished researcher in cardiovascular disease, she has made groundbreaking contributions to understanding the role of gut microbiota in hypertension and cardiovascular diseases. Dr. Li is a Youth member of the China Association for the Promotion of International Healthcare Exchanges and holds several key roles in cardiovascular physiology and vascular medicine groups. Her research, supported by the National Natural Science Foundation and Beijing Science Foundation, focuses on the pathological mechanisms and prevention of cardiovascular diseases. She has published over 28 SCI papers, significantly advancing knowledge in hypertension, gut microbiota, and cardiovascular pathophysiology.

Professional Profile

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🌟 Jing Li, PhD – Suitability for the Research for Best Researcher Award

Jing Li, PhD, Associate Professor at the Heart Center and Beijing Chaoyang Hospital, Capital Medical University, is an exemplary candidate for the Research for Best Researcher Award due to her pioneering contributions in cardiovascular research, particularly in the role of gut microbiota in hypertension and cardiovascular diseases. With a robust track record of presiding over major research projects such as those funded by the National Natural Science Foundation and Beijing Science Foundation, Dr. Li’s research addresses critical gaps in understanding the pathophysiology of hypertension through the lens of intestinal bacteria, offering innovative insights into disease prevention and management. Her work in elucidating the causal relationship between gut microbiota and hypertension is ground-breaking, highlighting the potential of microbiota as therapeutic targets in managing cardiovascular diseases.

Her impressive body of work includes 28 SCI papers published in high-impact journals such as Hypertension, Microbiome, and Gut Microbes, with a total impact factor of 175.8. Dr. Li’s published research on the dysbiosis of gut microbiota in hypertensive patients and its implications for cardiovascular health has had a profound impact on the field, particularly with publications like “Gut microbiota dysbiosis contributes to the development of hypertension” (Microbiome, 2017) and “Causality of Opportunistic Pathogen Klebsiella pneumoniae to Hypertension Development” (Hypertension, 2022).

πŸŽ“ EducationΒ 

Dr. Jing Li earned her PhD in Cardiovascular Physiology and Pathophysiology, specializing in hypertension and gut microbiota interactions. She pursued her academic journey at renowned institutions in China, where she honed her expertise in cardiovascular research and microbiology. Dr. Li’s academic background lays the foundation for her groundbreaking research on how the intestinal microbiome contributes to cardiovascular health. Her research interests reflect her commitment to advancing scientific knowledge in this critical field, with particular focus on the development of innovative preventive strategies against hypertension. Throughout her career, Dr. Li has also been involved in several collaborative projects with national research agencies, further enriching her knowledge and professional development.

πŸ’ΌΒ Β Professional ExperienceΒ 

Dr. Jing Li holds a prominent role at Beijing Chaoyang Hospital, where she leads significant cardiovascular research projects, particularly focusing on hypertension and gut microbiota. She has presided over several high-impact national projects, such as those funded by the National Natural Science Foundation and Beijing Science Foundation. As an associate professor and director of the China Medical and Microecology Integration Alliance, Dr. Li combines her leadership in academia with a strong commitment to practical, clinical applications of her research. Her position as a youth member of the China Association for the Promotion of International Healthcare Exchanges further underscores her influence in advancing international collaborations in cardiovascular health. She is also a deputy leader of the Cardiovascular Physiology and Pathophysiology Group of the Vascular Medicine Committee of the Beijing Physiological Science Society, shaping the future of cardiovascular medicine through innovation and education.

πŸ…Β Awards and Recognition

Dr. Jing Li’s exceptional research and contributions to cardiovascular disease have earned her recognition from various prestigious organizations. She has been awarded multiple honors for her work on hypertension, gut microbiota, and cardiovascular diseases. Her leadership in national research projects has led to a significant body of work that has been recognized globally. Dr. Li’s publications, with over 175.8 impact factors, are considered seminal in the field of cardiovascular disease and microbiome research. She has been invited to share her insights at several international conferences and has received numerous accolades for her innovative approach to tackling hypertension and other cardiovascular disorders. Her recognition extends to her roles as a director and expert advisor to national health organizations, where she provides valuable guidance on advancing the integration of medical research with practical healthcare solutions.

🌍 Research Skill On Cardiovascular Disease

Dr. Jing Li possesses advanced research skills in cardiovascular physiology, pathophysiology, and microbiome studies. She is an expert in exploring the connections between gut microbiota and cardiovascular diseases such as hypertension, a field where her work has opened new avenues for disease prevention. Her methodological expertise spans experimental design, microbiological analysis, and advanced statistical modeling. Dr. Li’s research combines cutting-edge laboratory techniques with clinical data, enabling her to bridge the gap between basic science and real-world health applications. She has demonstrated an exceptional ability to identify novel biomarkers, explore microbial mechanisms, and validate therapeutic targets for cardiovascular diseases. Her work integrates molecular biology, microbiology, and clinical medicine, positioning her as a leading researcher in her field. Dr. Li’s contributions to cardiovascular research are highly regarded, influencing the direction of future research in hypertension and related cardiovascular conditions.

πŸ“– Publication Top Notes

  • BBIBP-CorV Vaccination against the SARS-CoV-2 Virus Affects the Gut Microbiome
    • Authors: Yang Shen, Ying Dong, Jie Jiao, Pan Wang, Mulei Chen, Jing Li
    • Citation: Vaccines, 2023
  • Alterations of gut viral signals in atrial fibrillation: complex linkage with gut bacteriome
    • Authors: Zuo, Kun; Li, Jing; Fang, Chen; Zhong, Jiuchang; Xu, Li; Yang, Xinchun
    • Citation: Aging, 2022
  • Antihypertensive Therapy by ACEI/ARB Is Associated With Intestinal Flora Alterations and Metabolomic Profiles in Hypertensive Patients
    • Authors: Dong, Ying; Wang, Pan; Jiao, Jie; Yang, Xinchun; Chen, Mulei; Li, Jing
    • Citation: Frontiers in Cell and Developmental Biology, 2022
  • Causality of Opportunistic Pathogen Klebsiella pneumoniae to Hypertension Development
    • Authors: Li, Jing; Gao, Qiannan; Ma, Yiyangzi; Deng, Yue; Li, Shuangyue; Shi, Na; Niu, Haitao; Liu, Xin-Yu; Cai, Jun
    • Citation: Hypertension, 2022
  • Characterization of fecal metabolome changes in patients with obstructive sleep apnea
    • Authors: Dong, Ying; Wang, Pan; Lin, Junling; Han, Chunming; Jiao, Jie; Zuo, Kun; Chen, Mulei; Yang, Xinchun; Cai, Jun; Jiang, He et al.
    • Citation: Journal of Clinical Sleep Medicine, 2022
  • Characterization of the Intestinal Microbiome in Healthy Adults over Sars-Cov-2 Vaccination
    • Authors: Jiao, Jie; Shen, Yang; Wang, Pan; Zuo, Kun; Yang, Xinchun; Chen, Mulei; Dong, Ying; Li, Jing
    • Citation: Frontiers in Bioscience-Landmark, 2022
  • Kidney microbiota dysbiosis contributes to the development of hypertension
    • Authors: Liu, Xin-Yu; Li, Jing; Zhang, Yamei; Fan, Luyun; Xia, Yanli; Wu, Yongyang; Chen, Junru; Zhao, Xinyu; Gao, Qiannan; Xu, Bing et al.
    • Citation: Gut Microbes, 2022
  • Potential of gut microbiota for lipopolysaccharide biosynthesis in European women with type 2 diabetes based on metagenome
    • Authors: Dong, Ying; Wang, Pan; Yang, Xinchuan; Chen, Mulei; Li, Jing
    • Citation: Frontiers in Cell and Developmental Biology, 2022
  • Profile of gut flora in hypertensive patients with insufficient sleep duration
    • Authors: Jiao, Jie; Dong, Ying; Wang, Pan; Zuo, Kun; Han, Chunming; Cai, Jun; Zhong, Jiuchang; Yang, Xinchun; Li, Jing
    • Citation: Journal of Human Hypertension, 2022
  • Abnormal apelin-ACE2 and SGLT2 signaling contribute to adverse cardiorenal injury in patients with COVID-19
    • Authors: Li, Xue-Ting; Zhang, Mi-Wen; Zhang, Zhen-Zhou; Cao, Yu-Dan; Liu, Xiao-Yan; Miao, Ran; Xu, Yuan; Song, Xiao-Fang; Song, Jia-Wei; Liu, Ying et al.
    • Citation: International Journal of Cardiology, 2021

Sinenhlanhla Mthembu | Cardiovascular | Young Scientist Award

Ms. Sinenhlanhla Mthembu | Cardiovascular | Young Scientist Award

πŸ‘€Β Ms. Sinenhlanhla Mthembu, North-West University, South Africa

Sinenhlanhla Xoliswa Happiness Mthembu is a PhD candidate in Biochemistry at North-West University, specializing in dyslipidemia-associated myocardial dysfunction and cardioprotective effects of natural compounds like aspalathin and sulforaphane. With a strong foundation in Biochemistry and Microbiology, Sinenhlanhla has contributed significantly to the understanding of mitochondrial bioenergetics, oxidative stress, and metabolic diseases, especially related to cardiovascular health. Her research and dedication have earned her several prestigious awards and recognitions, such as the IUBMB MilliporeSigma ENABLE-Africa Fellowship and the South African Women in Science Award. She is a member of the South African Society of Biochemistry and Molecular Biology and the South African Heart Association.

Professional ProfileΒ 

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🌟  Suitability for the Award Research for Young Scientist Award

Sinenhlanhla Xoliswa Happiness Mthembu stands out as an ideal candidate for the Research for Young Scientist Award, owing to her impressive academic trajectory and pioneering contributions to the field of Biochemistry and Microbiology. Her current doctoral research on dyslipidemia-associated dysregulations and cardioprotective effects of aspalathin and sulforaphane, pursued at North-West University, is highly relevant and demonstrates a deep understanding of biochemical and mitochondrial bioenergetics. She has made significant strides in understanding the role of mitochondrial function in various diseases, especially in relation to cardiovascular and metabolic disorders, which showcases her scientific rigor.

In addition to her doctoral work, Mthembu has contributed extensively to scientific knowledge through numerous publications in renowned journals. Her research on the potential therapeutic roles of bioactive compounds like aspalathin and sulforaphane aligns with global health concerns, particularly in the areas of obesity, diabetes, and cardiovascular diseases. This breadth of work places her at the forefront of emerging research on metabolic diseases and therapeutic interventions.

πŸŽ“ EducationΒ 

Sinenhlanhla Mthembu’s educational journey reflects her dedication to advancing the field of Biochemistry. She completed her MSc in Biochemistry at the University of Zululand, where she explored the effect of Rooibos Polyphenols on mitochondrial function in skeletal muscles. Her undergraduate studies in Biochemistry and Microbiology laid a solid foundation for her research in molecular biology. She is currently pursuing a PhD at North-West University, investigating the cardioprotective effects of aspalathin and sulforaphane in the context of dyslipidemia. Her academic pursuits demonstrate a keen focus on cardiovascular health, oxidative stress, and mitochondrial bioenergetics, establishing her as a rising star in the scientific community.

πŸ’ΌΒ Β Professional ExperienceΒ 

Sinenhlanhla Mthembu’s professional journey is marked by her current role as a PhD intern fellow at the South African Medical Research Council (SAMRC), where she investigates the impact of dyslipidemia and metabolic diseases on heart function. Her previous experience as a laboratory assistant and demonstrator at North-West University further enhanced her expertise in molecular biology, biochemistry, and scientific research techniques. She has worked extensively with techniques such as RT-qPCR, Western blot analysis, flow cytometry, and Seahorse XF technology. Throughout her career, Sinenhlanhla has contributed to the development of therapeutic approaches to tackle diabetes, obesity, and cardiovascular diseases.

πŸ…Β Awards and RecognitionΒ 

Sinenhlanhla Mthembu’s excellence has been recognized with numerous awards and scholarships. She received the IUBMB MilliporeSigma ENABLE-Africa Fellowship in 2024, along with the South African Women in Science Award, which underscores her contributions to advancing women in science. Her outstanding presentation at the FEBS-IUBMB-ENABLE conference earned her the Outstanding Poster Award. Sinenhlanhla was also granted the SA Heart Congress Educational Grant to attend the 24th Annual SA Heart Congress. She has been awarded the SAMRC Scholarship Programme for both her PhD and MSc studies and has received the prestigious Top Achiever award from the Moses Kotane Institute and the University of Zululand.

🌍  Research Skills On Cardiovascular

Sinenhlanhla Mthembu possesses an array of advanced research skills, with a strong focus on Biochemistry and Molecular Biology. Her expertise includes Metagenomics sequencing, RT-qPCR, Western blot analysis, and flow cytometry. She has experience in scientific peer review and writing, as well as cell culture techniques. Sinenhlanhla is proficient in utilizing Seahorse XF technology and ELISA assays to evaluate metabolic changes at the cellular level. Her research focuses on dyslipidemia, mitochondrial dysfunction, oxidative stress, and the role of natural compounds like aspalathin and sulforaphane in combating metabolic diseases, particularly cardiovascular complications.

πŸ“– Publication Top Notes

  • Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature
    Authors: N Muvhulawa, PV Dludla, K Ziqubu, SXH Mthembu, F Mthiyane, …
    Citation: Pharmacological research 178, 106163
    Year: 2022
  • Detrimental effects of lipid peroxidation in type 2 diabetes: Exploring the neutralizing influence of antioxidants
    Authors: SC Shabalala, R Johnson, AK Basson, K Ziqubu, N Hlengwa, …
    Citation: Antioxidants 11 (10), 2071
    Year: 2022
  • A Review on the Antidiabetic Properties of Moringa oleifera Extracts: Focusing on Oxidative Stress and Inflammation as Main Therapeutic Targets
    Authors: FT Mthiyane, PV Dludla, K Ziqubu, SXH Mthembu, N Muvhulawa, …
    Citation: Frontiers in Pharmacology 13, 940572
    Year: 2022
  • An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin
    Authors: K Ziqubu, PV Dludla, SXH Mthembu, BB Nkambule, SE Mabhida, BU Jack, …
    Citation: Frontiers in Endocrinology 14, 1114767
    Year: 2023
  • Anti-obesity effects of metformin: a scoping review evaluating the feasibility of brown adipose tissue as a therapeutic target
    Authors: K Ziqubu, SE Mazibuko-Mbeje, SXH Mthembu, SE Mabhida, BU Jack, …
    Citation: International Journal of Molecular Sciences 24 (3), 2227
    Year: 2023
  • Impact of physical exercise and caloric restriction in patients with type 2 diabetes: Skeletal muscle insulin resistance and mitochondrial dysfunction as ideal therapeutic targets
    Authors: SXH Mthembu, SE Mazibuko-Mbeje, K Ziqubu, TA Nyawo, N Obonye, …
    Citation: Life Sciences 297, 120467
    Year: 2022
  • Physical exercise potentially targets epicardial adipose tissue to reduce cardiovascular disease risk in patients with metabolic diseases: Oxidative stress and inflammation
    Authors: TA Nyawo, C Pheiffer, SE Mazibuko-Mbeje, SXH Mthembu, …
    Citation: Antioxidants 10 (11), 1758
    Year: 2021
  • Impact of isoorientin on metabolic activity and lipid accumulation in differentiated adipocytes
    Authors: K Ziqubu, CJF Muller, PV Dludla, SXH Mthembu, N Obonye, J Louw, …
    Citation: Molecules 25 (8), 1773
    Year: 2020
  • A systematic review exploring the significance of measuring epicardial fat thickness in correlation to B-type natriuretic peptide levels as prognostic and diagnostic markers in
    Authors: TA Nyawo, PV Dludla, SE Mazibuko-Mbeje, SXH Mthembu, …
    Citation: Heart Failure Reviews, 1-11
    Year: 2022
  • Rooibos flavonoids, aspalathin, isoorientin, and orientin ameliorate antimycin A-induced mitochondrial dysfunction by improving mitochondrial bioenergetics in cultured skeletal
    Authors: SXH Mthembu, CJF Muller, PV Dludla, E Madoroba, AP Kappo, …
    Citation: Molecules 26 (20), 6289
    Year: 2021