Dr. Divya Rai, Knowledge Works Global Ltd, India
Divya Rai, a passionate scientist specializing in Endocrinology, holds a Ph.D. from CSIR-Central Drug Research Institute (CDRI), Lucknow. Her research focuses on investigating small molecules and miRNAs as potential bone anabolics, aiming to enhance bone formation and fracture healing. She has developed expertise in data analysis, manuscript preparation, and research methodologies, with three first-author articles and multiple co-authored publications. Divya is committed to advancing scientific literacy and dispelling myths in the public realm. Her work has positioned her as a key player in drug development for bone biology, contributing to the improvement of human health.
Professional Profile
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Suitability for the Research for Best Researcher Award
Divya Rai’s impressive academic and research journey in the field of biological sciences, specifically in endocrinology, makes her an excellent candidate for the “Research for Best Researcher Award.” Her doctoral research, focused on exploring the role of small molecules and cross-kingdom miRNAs as bone anabolics, has the potential to impact bone health significantly. By investigating galloyl conjugates of flavanones and miRNAs derived from food sources, Rai has contributed to a deeper understanding of bone biology, specifically in fracture healing and osteoporosis treatment.
Education
Divya Rai completed her Ph.D. in Endocrinology from CSIR-Central Drug Research Institute (CDRI) in 2024, specializing in bone anabolics and miRNA regulation. She earned an M.Sc. in Zoology from the University of Lucknow in 2016, graduating with 86.72%. Prior to that, she obtained a B.Sc. in Zoology, Botany, and Chemistry from the University of Lucknow in 2014. Divya’s academic foundation has provided a strong base for her advanced research in the field of bone biology. Throughout her studies, she demonstrated exceptional academic performance and a deep interest in scientific exploration. Her postgraduate and doctoral studies have equipped her with extensive knowledge in endocrinology, molecular biology, and biostatistics.
Professional Experience
Divya Rai has extensive research experience at CSIR-Central Drug Research Institute (CDRI) in Lucknow, where she has worked as a Junior Research Fellow, Senior Research Fellow, and now as a Senior Project Associate. She specializes in the development of formulations for bone health and fracture healing, with a focus on small molecules and cross-kingdom miRNAs. Divya has contributed significantly to the industrial-scale formulation of Ashwagandha-charged products aimed at enhancing bone health. Her research expertise extends to techniques like cell culture, PCR, histology, and immunohistochemistry. Additionally, she has served as a reviewer for numerous endocrine journals, showcasing her critical thinking and deep understanding of her field. Divya is also skilled in writing research grants, manuscripts, and protocols, further demonstrating her proficiency in scientific communication.
Awards and Recognition
Divya Rai has earned recognition for her research contributions in bone biology and endocrinology. Her expertise and dedication have been acknowledged through multiple presentations at international conferences, including the “Current Trends in Drug Discovery Research” in 2022 and the 17th Annual Conference of the Indian Society for Bone and Mineral Research (ISBMR) in 2021. She has also presented her work at the 90th Annual Meeting of the Society of Biological Chemists of India (SBC(I)) and the 103rd Indian Science Congress. Divya’s innovative research on small molecules and miRNAs has gained recognition in the scientific community, resulting in publications in esteemed journals. Her contributions to drug development for bone health have further established her as a leader in her field, continually fostering collaboration and the exchange of scientific knowledge.
Research Skills
Divya Rai is proficient in a wide range of research techniques, making her an expert in molecular biology and endocrinology. Her skills include cell culture, in-vitro transfection, Micro-CT, and histology, enabling her to conduct comprehensive studies in bone biology. She is adept in PCR, immunohistochemistry, and Western blotting, techniques essential for protein and gene analysis. Divya’s research expertise extends to osteotomy, ovariectomy, and ligament transection surgery in rats, highlighting her capability in animal studies. She has also demonstrated proficiency in ELISA for biomarker analysis and Biostatistics for experimental design and data analysis. Her work on cross-kingdom gene regulation in osteoblasts and its implications for bone health further underscores her research versatility. Divya is skilled in preparing scientific grants, research protocols, and manuscripts, solidifying her role as a proficient communicator of complex scientific concepts.
Publication Top Notes
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miR4352b a cross-species modulator of SOSTDC1, targets dual pathway to regulate bone health and fracture healing.
- Authors: Rai D, Anirban Sardar, Raj A, Maji B, Verma S, Ashish Kumar Tripathi, Gupta S, Sharma A, Dhar YV, Trivedi R
- Citation: Biochimica et Biophysica Acta – Molecular Basis of Disease, 2024-09-24
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Withaferin A Ameliorated the Bone Marrow Fat Content in Obese Male Mice by Favoring Osteogenesis in Bone Marrow Mesenchymal Stem Cells and Preserving the Bone Mineral Density.
- Authors: Ashish Kumar Tripathi, Anirban Sardar, Rai N, Rai D, Aboli Girme, Sinha S, Chutani K, Hingorani L, PR Mishra, Prabhat Mishra, Ritu Trivedi
- Citation: ACS Pharmacology & Translational Science, 2024-08-19
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A glucuronated flavone TMMG spatially targets chondrocytes to alleviate cartilage degeneration through negative regulation of IL-1β.
- Authors: Priyanka Kothari, Geeta Dhaniya, Anirban Sardar, Shradha Sinha, Aboli Girme, Divya Rai, Kunal Chutani, Lal Hingorani, Ritu Trivedi
- Citation: Biomedicine & Pharmacotherapy, 2023-07
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Design, synthesis and biological evaluation of new quinazolinone-benzopyran-indole hybrid compounds promoting osteogenesis through BMP2 upregulation.
- Authors: Anirban Sardar, Alisha Ansari, Sampa Gupta, Shradha Sinha, Shubham Pandey, Divya Rai, Mukesh Kumar, Rabi Sankar Bhatta, Ritu Trivedi, Koneni V. Sashidhara
- Citation: European Journal of Medicinal Chemistry, 2022-12
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Nanoparticles of naturally occurring PPAR-γ inhibitor betulinic acid ameliorates bone marrow adiposity and pathological bone loss in ovariectomized rats via Wnt/β-catenin pathway.
- Authors: Anirban Sardar, Gautam S, Sinha S, Rai D, Ashish Kumar Tripathi, Dhaniya G, Mishra PR, Ritu Trivedi
- Citation: Life Sciences, 2022-09-30