Prof. Paula Guedes de Pinho | Pharmacology, Toxicology and Pharmaceutical Science |Outstanding Scientist Award

Prof. Paula Guedes de Pinho | Pharmacology, Toxicology and Pharmaceutical Science |Outstanding Scientist Award

professor Paula Guedes de Pinho Faculdade de Farmácia da Universidade do Porto, Portugal

Author Profile

Dr. Maria Paula do Amaral Alegria Guedes de Pinho (PGP): Leading Cancer Metabolomics Researcher 🧬🔬

Dr. Maria Paula do Amaral Alegria Guedes de Pinho, commonly known as PGP, is a distinguished researcher and academic in the field of cancer metabolomics. She holds a prominent position at the Faculty of Pharmacy of Porto University (FFUP) and is affiliated with UCIBIO – Applied Molecular Biosciences Unit.

🎓 Education & Training

  • Habilitation in Toxicology: Faculty of Pharmacy, University of Porto, April 2019.
  • Ph.D. in Biomedical Sciences: University of Bordeaux II, France, June 1991 – December 1994.
  • M.Sc. in Pharmaceutical Sciences: Faculty of Pharmacy, University of Porto, September 1989 – July 1990.

🏫 Academic and Research Positions

  • Permanent Contract Researcher: Faculty of Pharmacy, University of Porto, January 2023 – present.
  • Coordinating Researcher: UCIBIO/REQUIMTE (ICETA) at Faculty of Pharmacy, University of Porto, specializing in cancer metabolomics, January 2016 – present.
  • Affiliate Professor: Faculty of Sciences, University of Porto, teaching Metabolomics at the Master in Bioinformatics and Computational program, April 2022 – present.
  • Assistant Professor: Portuguese Catholic University, School of Biotechnology – Porto (ESB-UCP), September 2001 – May 2005.

🌟 Research Contributions

PGP has significantly contributed to the field of metabolomics, particularly in cancer biomarker discovery. She has published over 200 papers in international peer-reviewed journals, 13 book chapters, and has received 15 prizes or awards. Her research has notably advanced the understanding of cancer through the application of metabolomics.

📊 Grants and Major Projects

One of her notable projects includes:

  • Project No. 30388-SAICT 2017-ACCUSED: “RenAl Cell Carcinoma Detection Renal Cancer detection: a translational metabolomics research based on Volatile Organic Compounds fingerprinting”, funded by the Foundation for Science and Technology (FCT) and the Portugal 2020 Program, with a budget of €239,499.09 (2018-2021) (Principal Investigator).

📚 Editorial and Evaluator Roles

PGP holds editorial board positions in five international journals and is actively involved as a member of scholarship and research project evaluation committees. She is also part of the Agência de Investigação Clínica e Inovação Biomédica (AICIB) and unCAN.eu Delphi group, contributing to the advancement of biomedical innovation and clinical research.

Publication Top Noted:🏅

Paper Title: Khat and synthetic cathinones: a review

  • Authors: MJ Valente, P Guedes de Pinho, M de Lourdes Bastos, F Carvalho, …
  • Journal: Archives of Toxicology
  • Volume: 88
  • Issue:
  • Pages: 15-45
  • Year: 2014

Paper Title: Metabolomics analysis for biomarker discovery: advances and challenges

  • Authors: MS Monteiro, M Carvalho, ML Bastos, P Guedes de Pinho
  • Journal: Current Medicinal Chemistry
  • Volume: 20
  • Issue: 2
  • Pages: 257-271
  • Year: 2013

Paper Title: The hallucinogenic world of tryptamines: an updated review

  • Authors: AM Araújo, F Carvalho, ML Bastos, P Guedes de Pinho, M Carvalho
  • Journal: Archives of Toxicology
  • Volume: 89
  • Issue:
  • Pages: 1151-1173
  • Year: 2015

Paper Title: Heavy sulphur compounds, higher alcohols and esters production profile of Hanseniaspora uvarum and Hanseniaspora guilliermondii grown as pure and mixed cultures in grape must

  • Authors: N Moreira, F Mendes, PG de Pinho, T Hogg, I Vasconcelos
  • Journal: International Journal of Food Microbiology
  • Volume: 124
  • Issue: 3
  • Pages: 231-238
  • Year: 2008

Paper Title: Identification of key odorants related to the typical aroma of oxidation-spoiled white wines

  • Authors: AC Silva Ferreira, T Hogg, P Guedes de Pinho
  • Journal: Journal of Agricultural and Food Chemistry
  • Volume: 51
  • Issue: 5
  • Pages: 1377-1381
  • Year: 2003

Paper Title: Fatty acid composition of wild edible mushrooms species: A comparative study

  • Authors: B Ribeiro, PG de Pinho, PB Andrade, P Baptista, P Valentão
  • Journal: Microchemical Journal
  • Volume: 93
  • Issue: 1
  • Pages: 29-35
  • Year: 2009

Paper Title: Amanita phalloides poisoning: Mechanisms of toxicity and treatment

  • Authors: J Garcia, VM Costa, A Carvalho, P Baptista, PG de Pinho, …
  • Journal: Food and Chemical Toxicology
  • Volume: 86
  • Issue:
  • Pages: 41-55
  • Year: 2015

Paper Title: Correlation between the pattern volatiles and the overall aroma of wild edible mushrooms

  • Authors: PG Pinho, B Ribeiro, RF Gonçalves, P Baptista, P Valentão, RM Seabra, …
  • Journal: Journal of Agricultural and Food Chemistry
  • Volume: 56
  • Issue: 5
  • Pages: 1704-1712
  • Year: 2008

Paper Title: Biomarker discovery in human prostate cancer: an update in metabolomics studies

  • Authors: AR Lima, M de Lourdes Bastos, M Carvalho, PG de Pinho
  • Journal: Translational Oncology
  • Volume: 9
  • Issue: 4
  • Pages: 357-370
  • Year: 2016

Paper Title: Glycine max (L.) Merr., Vigna radiata L. and Medicago sativa L. sprouts: A natural source of bioactive compounds

  • Authors: LR Silva, MJ Pereira, J Azevedo, RF Gonçalves, P Valentão, PG de Pinho, …
  • Journal: Food Research International
  • Volume: 50
  • Issue: 1
  • Pages: 167-175
  • Year: 2013

ROHIT BHATIA | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

ROHIT BHATIA | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

ISF College of Pharmacy Moga, India

Author Profile

Early Academic Pursuits

Dr. Rohit Bhatia embarked on his academic journey with a B. Pharmacy degree from HP University, graduating with an impressive 75.5% in 2011. Building on this foundation, he pursued a Master's in Pharmacy in Pharmaceutical Chemistry from PTU University, securing a notable 74.5% in 2013. His academic pursuit culminated in a Ph.D. in Pharmaceutical Sciences from MRSPTU, Bathinda, in 2022, showcasing his dedication to advancing in the field.

Professional Endeavors

HIs professional career is marked by significant milestones. He served as an Assistant Professor of Pharmaceutical Chemistry at Laureate Institute of Pharmacy from 2013 to 2016 before transitioning to his current role as an Associate Professor at ISF College of Pharmacy from 2016 to the present. His roles have involved guiding numerous M. Pharm and Ph.D. students, totaling 27 and 3, respectively, showcasing his commitment to mentorship and education in the pharmaceutical field.

Contributions and Research Focus

With a keen interest in drug design and molecular modeling, His contributed significantly to pharmaceutical sciences. His research projects, including the synthesis and evaluation of coumarin fused/tethered nitrogen-containing heterocycles as anticancer agents and work on imidazo [2,1-b] [1,3,4] thiadiazole derivatives, highlight his expertise in synthetic medicinal chemistry and target-based drug design. Furthermore, his focus on analytical method development and bioanalysis, along with microfluidics-based analysis, underscores his multidisciplinary approach to research.

Accolades and Recognition

His contributions have been widely recognized through various grants, awards, and achievements. Notable among these are the MSME grant for developing an electrochemical device for detecting glucose levels in human saliva, received in 2022. His innovative teaching methods earned him the Best Innovative Teacher Award in Pharmaceutical Analysis at the National Pharma Summit-2023. Additionally, he has consistently won prizes and awards for his research presentations, such as the Pharma Rising Star Award and recognition for his work in repurposing drugs against SARS-CoV-2.

Impact and Influence

His work has made a tangible impact on the pharmaceutical landscape, evident from his patents and copyrights. His patents range from techniques for quantifying ascorbic acid to novel drug delivery systems and neuroprotective compounds, showcasing his diverse contributions to the field. Furthermore, his involvement in national and international conferences, along with his role as a Bentham Ambassador, speaks volumes about his influence and standing within the scientific community.

Legacy and Future Contributions

His continues to excel in academia and research, his legacy as a mentor, innovator, and contributor to pharmaceutical sciences is firmly established. His future contributions are anticipated to further push the boundaries of drug design, analytical techniques, and therapeutic innovations. Through his continued dedication to education, research, and impactful collaborations, His  is poised to leave a lasting imprint on the field of pharmaceutical sciences.

Notable Publications 

Synthetic and medicinal perspective of thiazolidinones: A review

Drug metabolizing enzymes and their inhibitors' role in cancer resistance

Inductively coupled plasma optical emission spectrometry (ICP-OES): a powerful analytical technique for elemental analysis

Applications of various analytical techniques in quality control of pharmaceutical excipients

Design, synthesis and neuropharmacological evaluation of new 2, 4-disubstituted-1, 5-benzodiazepines as CNS active agents

Protein tyrosine phosphatase (PTP1B): a promising drug target against life-threatening ailments

based microfluidic devices: Fabrication, detection, and significant applications in various fields

Recent advancements in anti-leishmanial research: Synthetic strategies and structural activity relationships

Enasidenib: first mutant IDH2 inhibitor for the treatment of refractory and relapsed acute myeloid leukemia

Design, synthesis, biological evaluation, and molecular modeling studies of rhodanine derivatives as pancreatic lipase inhibitors