Sijoon Lee | Pathology | Best Researcher Award

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Dr. Sijoon Lee | Pathology | Best Researcher Award

Dr. Sijoon Lee, Daegu-Gyeongbuk Medical Innovation Foundation, South Korea

Sijoon Lee is a veterinary biomedical scientist with a Ph.D. from Gyeongsang National University, specializing in microplastic toxicity and exosome-based therapeutics. With over a decade of research and toxicological pathology experience, he has pioneered studies on the effects of microplastics and extracellular vesicles in various biomedical fields. Currently a researcher at the Daegu-Gyeongbuk Medical Innovation Foundation in South Korea, Dr. Lee has contributed significantly to advancing knowledge in toxicology and the development of therapeutic approaches for diseases such as osteoporosis and idiopathic pulmonary fibrosis. His innovative work has earned him recognition in high-impact journals.

Professional Profile

Scopus

Suitability for the Research for Best Researcher Award

Sijoon Lee is highly suitable for the Research for Best Researcher Award based on his extensive contributions to biomedical research, particularly in the areas of microplastic toxicity, exosome-based therapeutics, and osteoporosis treatments. With over 10 years of research experience, Dr. Lee has demonstrated a deep understanding of toxicological pathology and biomedical science. His projects—ranging from the evaluation of drug safety and efficacy to the development of technology for harmful substance evaluation—highlight his innovative approach to addressing critical health issues.

Dr. Lee’s work has made a significant impact, reflected in the publication of over 30 high-impact journal articles and the citation of his research more than 50 times. Notably, his groundbreaking work in microplastic toxicity and the development of therapeutic interventions using exosome-derived technologies has the potential to revolutionize biomedical treatment options. His contributions to drug safety evaluation, especially in collaboration with pharmaceutical companies, also underscore his excellence in translational research, making his work both impactful and relevant.

Education 🎓

Dr. Sijoon Lee obtained his Ph.D. in Veterinary Biomedical Science from Gyeongsang National University. His academic journey has been focused on the intersection of pathology, toxicology, and biomedical innovations, particularly in the study of microplastics and exosome-based therapies. His rigorous training laid the foundation for his research on the safety and efficacy of drug treatments, including those related to osteoporosis. His continuous pursuit of knowledge in toxicological pathology has earned him multiple memberships in prestigious scientific societies and recognition as an expert in his field.

Professional Experience 💼

Dr. Sijoon Lee has over ten years of experience in toxicological pathology and biomedical research. He is currently a researcher at the Daegu-Gyeongbuk Medical Innovation Foundation in South Korea, where he leads research projects on microplastic toxicity, drug efficacy for osteoporosis, and the development of therapeutic medical devices. Dr. Lee has supported several pharmaceutical and biotech companies in their R&D efforts, particularly in conducting toxicity studies and efficacy evaluations. His contributions to the pharmaceutical sector include providing pathological evaluations for FDA/MFDS compliance in preclinical studies and supporting osteoporosis drug development.

Awards and Recognition 🏅

Dr. Sijoon Lee’s research excellence has been acknowledged with numerous accolades, including over 50 citations for his works published in high-impact journals such as International Journal of Molecular Sciences and Polymers. He has received recognition for his contributions to the fields of microplastic toxicity, exosome-based therapeutics, and biomedical research. In addition, Dr. Lee holds multiple granted patents, such as “Composition for the prevention or treatment of liver disease containing fat extract of Gwamegi” and “Stress diagnostic technology using exosome-derived miRNAs.” He is a highly regarded member of multiple toxicology and veterinary societies.

Research Skills On Pathology 🌍

Dr. Sijoon Lee’s research expertise lies in the areas of microplastic toxicity, exosome-based therapeutics, and osteopathic treatments using stem cell-derived extracellular vesicles. His work focuses on understanding the toxicity and biodistribution of microplastics, developing biomarkers for diseases, and advancing the pharmacokinetics of medical materials. Additionally, Dr. Lee has contributed to neurobiology research and nerve regeneration mechanisms. His research aims to improve therapeutic outcomes for diseases like osteoporosis and idiopathic pulmonary fibrosis through cutting-edge biomedical technologies.

Publication Top Notes 📖

  • Title: Osteological analysis of Nyctereutes procyonoides bones excavated from the Gasan-ri archaeological site
    Authors: Lee, S., Choi, J., Won, C.
    Journal: Korean Journal of Veterinary Research
    Year: 2024
    Volume: 64
    Issue: 4
    Article ID: e34
  • Title: Spontaneous type II cell-derived bronchioloalveolar adenoma in a young ICR mouse
    Authors: Sung, M., Sung, S.-E., Choi, J.-H., Kim, D., Lee, S.
    Journal: Laboratory Animals
    Year: 2024
    Volume: 58
    Issue: 6
    Pages: 621–625
  • Title: Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis
    Authors: Sung, S.-E., Lim, J.-H., Kang, K.-K., Seo, M.-S., Lee, G.W.
    Journal: Clinical Proteomics
    Year: 2024
    Volume: 21
    Issue: 1
    Article ID: 39
  • Title: Extracellular Vesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells Suppress RANKL-Induced Osteoclast Differentiation via miR122-5p
    Authors: Choi, J.-H., Sung, S.-E., Kang, K.-K., Seo, M.-S., Lee, G.W.
    Journal: Biochemical Genetics
    Year: 2024
    Volume: 62
    Issue: 4
    Pages: 2830–2852
  • Title: Investigation of prunetrin induced G2/M cell cycle arrest and apoptosis via Akt/mTOR/MAPK pathways in hepatocellular carcinoma cells
    Authors: Abusaliya, A., Bhosale, P.B., Kim, H.H., Lee, S., Kim, G.S.
    Journal: Biomedicine and Pharmacotherapy
    Year: 2024
    Volume: 174
    Article ID: 116483
  • Title: Enhanced Dural Repair Using Biodegradable Sealants Based on Photocurable Hyaluronic Acid
    Authors: Lee, H., Lee, S., Seong, K.-Y., Nam, K.H., Yang, S.Y.
    Journal: Macromolecular Bioscience
    Year: 2024
    Volume: 24
    Issue: 4
    Article ID: 2300359
  • Title: Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells
    Authors: Abusaliya, A., Kim, H.H., Vetrivel, P., Lee, S.J., Kim, G.S.
    Journal: Frontiers in Pharmacology
    Year: 2024
    Volume: 15
    Article ID: 1400186
  • Title: Antioxidant and Antimelanogenic Activities of Lactobacillus kunkeei NCHBL-003 Isolated from Honeybees
    Authors: Lee, Y.-J., Choi, J.-H., Kang, K.-K., Seo, M.-S., Park, J.-H.
    Journal: Microorganisms
    Year: 2024
    Volume: 12
    Issue: 1
    Article ID: 188
  • Title: Discovery and Feasibility Study of Medical Fluorophore 33 as a Novel Theranostic Agent
    Authors: Son, K.H., Lee, D.S., Park, G., Kim, D.-S., Jeon, Y.H.
    Journal: ACS Applied Materials and Interfaces
    Year: 2023
    Volume: 15
    Issue: 39
    Pages: 45539–45548
  • Title: Toxicity and Biodistribution of Fragmented Polypropylene Microplastics in ICR Mice
    Authors: Lee, S., Kim, D., Kang, K.-K., Kim, H.-K., Kim, K.
    Journal: International Journal of Molecular Sciences
    Year: 2023
    Volume: 24
    Issue: 10
    Article ID: 846

FANCY GAETE | Medicine | Women Researcher Award

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Dr. FANCY GAETE | Medicine | Women Researcher Award

👤 Dr. FANCY GAETE, HOSPITAL SANTIAGO ORIENTE DR. LUIS TISNÉ BROUSSE, Chile

Dr. Fancy Gaete Verdejo is a renowned anatomopathologist with 26 years of experience in Chile’s public healthcare system. As a pioneer in breast cancer diagnostics, she established the national reference center for the in situ hybridization technique for HER2 testing, which has been operational since 2011. In 2022, she transitioned from the manual FISH HER2 technique to the automated DISH HER2 method, integrating digital pathology and AI algorithms. This innovation led to a 13.02% reduction in costs, an 83.86% improvement in response time, and an 11.29% increase in productivity. Dr. Gaete is actively involved in the advancement of pathology practices and plays a leadership role as the President of the Chilean Society of Pathological Anatomy and the Chilean Society of Mastology.

Professional Profile

Scopus

🌟  Assessment of Suitability for the Research for Women Researcher Award

Summary of Suitability
Dr. Fancy Gaete Verdejo exemplifies an exceptional commitment to advancing research and innovation in pathology, specifically breast cancer diagnostics, within the Chilean public health system. Her pioneering efforts to centralize the HER2 in situ hybridization technique have significantly impacted breast cancer pathology in Chile. By introducing the automated DISH HER2 technique integrated with digital pathology and artificial intelligence (AI) algorithms, she has revolutionized diagnostic efficiency, reducing costs by 13.02%, cutting response times by 83.86%, and improving productivity by 11.29%.

Dr. Verdejo’s leadership in developing a national reference center for HER2 analysis has not only elevated the quality of public healthcare but also fostered a data-driven approach to diagnostics. Her dedication to reducing healthcare disparities through affordable and accessible diagnostic innovations underscores her suitability for this award. Moreover, her current roles as President of the Chilean Society of Pathological Anatomy and the Chilean Society of Mastology further highlight her influence and commitment to the field.

🎓  Education

Dr. Gaete completed her medical studies at the University of Chile, where she specialized in Anatomopathology. Her passion for advancing medical diagnostics led her to focus on molecular pathology, particularly in breast cancer. She further honed her skills by obtaining advanced training in digital pathology and artificial intelligence (AI) techniques, ensuring she stayed at the forefront of technological innovations in the field. Throughout her career, Dr. Gaete has pursued continuous education, contributing significantly to the implementation of cutting-edge technologies in public health systems. Her work has not only reshaped breast cancer diagnostic processes but has also inspired others in the field to incorporate AI and digital tools to improve healthcare outcomes.

💼  Professional Experience 

Dr. Fancy Gaete Verdejo has dedicated over 26 years of service in the Chilean public healthcare system. As an anatomopathologist, she has specialized in the diagnosis of breast cancer, implementing groundbreaking techniques and driving efficiency in pathology labs. In 2011, she established the national reference center for HER2 in situ hybridization in breast cancer, advancing diagnostic capabilities. Dr. Gaete’s work became more impactful in 2022 when she led the transition from manual FISH HER2 testing to an automated DISH HER2 method, integrating digital pathology with AI algorithms. This transition dramatically improved the turnaround time, reduced costs, and enhanced productivity within the system. Beyond her technical expertise, Dr. Gaete holds leadership roles in major Chilean medical societies, such as the Chilean Society of Pathological Anatomy and the Chilean Society of Mastology, where she contributes to the shaping of national health policies.

🏅  Awards and Recognition

Dr. Gaete’s pioneering contributions have earned her numerous accolades throughout her distinguished career. She has been recognized for her role in advancing breast cancer diagnostics in Chile, particularly through her development of the national reference center for HER2 in situ hybridization. Her innovative work in integrating digital pathology with AI has also been widely acknowledged for improving diagnostic accuracy and system efficiency. Additionally, Dr. Gaete’s leadership in the Chilean Society of Pathological Anatomy (President 2023-2026) and the Chilean Society of Mastology (President 2024-2026) reflects the esteem in which she is held by her peers. These positions have enabled her to influence national healthcare policies and standards in pathology and oncology. Her work has also led to several collaborations with international institutions, further expanding her impact on the global healthcare community.

🌍  Research Skills On Medicine

Dr. Gaete is an expert in anatomical pathology with a deep focus on molecular and digital pathology, particularly in breast cancer. Her research skills include a solid understanding of diagnostic techniques, data analysis, and the integration of innovative technologies such as artificial intelligence (AI) and digital imaging into pathology workflows. She excels in evaluating the economic impact of medical technologies, particularly in healthcare systems. Her research has significantly influenced the adoption of digital pathology and AI in Chile, demonstrating how these tools can optimize diagnostic precision and efficiency. Furthermore, Dr. Gaete is highly skilled in research management, leading both academic and industry collaborations. Her work has contributed to the publication of influential studies on the cost-effectiveness of healthcare technologies, such as her ongoing research on the economic impact of integrative digital pathology in public breast cancer diagnostics.

📖 Publication Top Notes

  • Impact of the Chilean explicit guarantees health system (GES) on breast cancer treatment | Resultados del tratamiento del cáncer de mama, programa nacional de cáncer del adulto
    • Authors: Castillo, C.S.M., Cabrera, M.E.C., Derio P., L., Gaete V., F., Cavada CH., G.
    • Journal: Revista Medica de Chile
    • Year: 2017
    • Volume: 145(12)
    • Pages: 1507–1513
    • Citations: 14
  • Spontaneous quadruplet pregnancy. A challenge for the multidisciplinary team in a health service | Gestación cuádruple espontánea. Un desafío para el equipo multidisciplinario en un servicio de salud
    • Authors: Salgado M., E., Lattus O., J., Barrera C., V., Fritis L., A., Gaete V., F.
    • Journal: Revista Chilena de Obstetricia y Ginecologia
    • Year: 2006
    • Volume: 71(1)
    • Pages: 35–42
    • Citations: 1
  • Jejunal diverticulosis as cause of gastrointestinal hemorrhages. Case report | Diverticulosis yeyunal: Una causa infrecuente de hemorragia digestiva. Caso clínico
    • Authors: Zapata L., R., Rojas S., C., Gaete V., F.
    • Journal: Revista Medica de Chile
    • Year: 2000
    • Volume: 128(10)
    • Pages: 1133–1138
    • Citations: 4