Prof. Paula Guedes de Pinho | Pharmacology, Toxicology and Pharmaceutical Science |Outstanding Scientist Award

Prof. Paula Guedes de Pinho | Pharmacology, Toxicology and Pharmaceutical Science |Outstanding Scientist Award

professor Paula Guedes de Pinho Faculdade de Farmácia da Universidade do Porto, Portugal

Author Profile

Dr. Maria Paula do Amaral Alegria Guedes de Pinho (PGP): Leading Cancer Metabolomics Researcher 🧬🔬

Dr. Maria Paula do Amaral Alegria Guedes de Pinho, commonly known as PGP, is a distinguished researcher and academic in the field of cancer metabolomics. She holds a prominent position at the Faculty of Pharmacy of Porto University (FFUP) and is affiliated with UCIBIO – Applied Molecular Biosciences Unit.

🎓 Education & Training

  • Habilitation in Toxicology: Faculty of Pharmacy, University of Porto, April 2019.
  • Ph.D. in Biomedical Sciences: University of Bordeaux II, France, June 1991 – December 1994.
  • M.Sc. in Pharmaceutical Sciences: Faculty of Pharmacy, University of Porto, September 1989 – July 1990.

🏫 Academic and Research Positions

  • Permanent Contract Researcher: Faculty of Pharmacy, University of Porto, January 2023 – present.
  • Coordinating Researcher: UCIBIO/REQUIMTE (ICETA) at Faculty of Pharmacy, University of Porto, specializing in cancer metabolomics, January 2016 – present.
  • Affiliate Professor: Faculty of Sciences, University of Porto, teaching Metabolomics at the Master in Bioinformatics and Computational program, April 2022 – present.
  • Assistant Professor: Portuguese Catholic University, School of Biotechnology – Porto (ESB-UCP), September 2001 – May 2005.

🌟 Research Contributions

PGP has significantly contributed to the field of metabolomics, particularly in cancer biomarker discovery. She has published over 200 papers in international peer-reviewed journals, 13 book chapters, and has received 15 prizes or awards. Her research has notably advanced the understanding of cancer through the application of metabolomics.

📊 Grants and Major Projects

One of her notable projects includes:

  • Project No. 30388-SAICT 2017-ACCUSED: “RenAl Cell Carcinoma Detection Renal Cancer detection: a translational metabolomics research based on Volatile Organic Compounds fingerprinting”, funded by the Foundation for Science and Technology (FCT) and the Portugal 2020 Program, with a budget of €239,499.09 (2018-2021) (Principal Investigator).

📚 Editorial and Evaluator Roles

PGP holds editorial board positions in five international journals and is actively involved as a member of scholarship and research project evaluation committees. She is also part of the Agência de Investigação Clínica e Inovação Biomédica (AICIB) and unCAN.eu Delphi group, contributing to the advancement of biomedical innovation and clinical research.

Publication Top Noted:🏅

Paper Title: Khat and synthetic cathinones: a review

  • Authors: MJ Valente, P Guedes de Pinho, M de Lourdes Bastos, F Carvalho, …
  • Journal: Archives of Toxicology
  • Volume: 88
  • Issue:
  • Pages: 15-45
  • Year: 2014

Paper Title: Metabolomics analysis for biomarker discovery: advances and challenges

  • Authors: MS Monteiro, M Carvalho, ML Bastos, P Guedes de Pinho
  • Journal: Current Medicinal Chemistry
  • Volume: 20
  • Issue: 2
  • Pages: 257-271
  • Year: 2013

Paper Title: The hallucinogenic world of tryptamines: an updated review

  • Authors: AM Araújo, F Carvalho, ML Bastos, P Guedes de Pinho, M Carvalho
  • Journal: Archives of Toxicology
  • Volume: 89
  • Issue:
  • Pages: 1151-1173
  • Year: 2015

Paper Title: Heavy sulphur compounds, higher alcohols and esters production profile of Hanseniaspora uvarum and Hanseniaspora guilliermondii grown as pure and mixed cultures in grape must

  • Authors: N Moreira, F Mendes, PG de Pinho, T Hogg, I Vasconcelos
  • Journal: International Journal of Food Microbiology
  • Volume: 124
  • Issue: 3
  • Pages: 231-238
  • Year: 2008

Paper Title: Identification of key odorants related to the typical aroma of oxidation-spoiled white wines

  • Authors: AC Silva Ferreira, T Hogg, P Guedes de Pinho
  • Journal: Journal of Agricultural and Food Chemistry
  • Volume: 51
  • Issue: 5
  • Pages: 1377-1381
  • Year: 2003

Paper Title: Fatty acid composition of wild edible mushrooms species: A comparative study

  • Authors: B Ribeiro, PG de Pinho, PB Andrade, P Baptista, P Valentão
  • Journal: Microchemical Journal
  • Volume: 93
  • Issue: 1
  • Pages: 29-35
  • Year: 2009

Paper Title: Amanita phalloides poisoning: Mechanisms of toxicity and treatment

  • Authors: J Garcia, VM Costa, A Carvalho, P Baptista, PG de Pinho, …
  • Journal: Food and Chemical Toxicology
  • Volume: 86
  • Issue:
  • Pages: 41-55
  • Year: 2015

Paper Title: Correlation between the pattern volatiles and the overall aroma of wild edible mushrooms

  • Authors: PG Pinho, B Ribeiro, RF Gonçalves, P Baptista, P Valentão, RM Seabra, …
  • Journal: Journal of Agricultural and Food Chemistry
  • Volume: 56
  • Issue: 5
  • Pages: 1704-1712
  • Year: 2008

Paper Title: Biomarker discovery in human prostate cancer: an update in metabolomics studies

  • Authors: AR Lima, M de Lourdes Bastos, M Carvalho, PG de Pinho
  • Journal: Translational Oncology
  • Volume: 9
  • Issue: 4
  • Pages: 357-370
  • Year: 2016

Paper Title: Glycine max (L.) Merr., Vigna radiata L. and Medicago sativa L. sprouts: A natural source of bioactive compounds

  • Authors: LR Silva, MJ Pereira, J Azevedo, RF Gonçalves, P Valentão, PG de Pinho, …
  • Journal: Food Research International
  • Volume: 50
  • Issue: 1
  • Pages: 167-175
  • Year: 2013

Pradip Nirbhavane | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Pradip Nirbhavane | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Amity University, India

Author Profile

Early Academic Pursuits

Dr. Pradip Nirbhavane embarked on an illustrious academic journey starting with a Bachelor of Pharmacy from the University of Pune, where he demonstrated exceptional competence with an average of 60.95%. His pursuit of excellence continued at NIPER, SAS Nagar, where he earned an M.S. (Pharm) degree with a notable 7.1 CGPA. This solid academic foundation paved the way for his significant contributions in the field of pharmaceuticals.

Professional Endeavors

His professional journey began as a Senior Research Fellow at Lifecare Innovations Pvt Ltd, where he contributed for nearly three years. Subsequently, he joined Intas Pharmaceuticals Ltd as an Assistant Manager, accumulating valuable industry experience for over two years. Currently, he serves as an Assistant Professor at Amity University, Gurgaon, where he imparts knowledge and fosters academic growth.

Contributions and Research Focus

His research focus encompasses nanotechnology and drug delivery, with a particular emphasis on topical, oral, and parenteral drug administration. His groundbreaking work includes novel discoveries and advancements in treating conditions like Onychomycosis and uveitis, as evidenced by his publications in esteemed journals such as Advanced Drug Delivery Reviews, International Ophthalmology, and Colloids and Surfaces B: Biointerfaces.

Accolades and Recognition

Throughout his career, Dr. Nirbhavane has been honored with prestigious awards, including the "Korean Ginseng Society-International Young Scientist" award and the "University of Birmingham India Institute Fellowship." These accolades underscore his exceptional contributions and recognition within the global scientific community.

Impact and Influence

His research has made a significant impact on the pharmaceutical landscape, particularly in enhancing drug bioavailability, targeted delivery, and therapeutic efficacy. His work on lipid nanocarriers and nanostructured formulations has opened new avenues for more effective and personalized treatments across various medical conditions.

Legacy and Future Contributions

With a legacy of impactful research and academic excellence, His continues to inspire future generations of pharmaceutical scientists. His dedication to quality research, innovative methodologies, and collaborative initiatives ensures a promising future characterized by advancements in drug delivery systems and improved patient outcomes.

Notable Publications 

Galactose engineered solid lipid nanoparticles for targeted delivery of doxorubicin

Quality by Design (QbD)-enabled development of aceclofenac loaded-nano structured lipid carriers (NLCs): An improved dermatokinetic profile for inflammatory disorder (s)

Nanostructured lipid carrier mediates effective delivery of methotrexate to induce apoptosis of rheumatoid arthritis via NF-κB and FOXO1

Fucose decorated solid-lipid nanocarriers mediate efficient delivery of methotrexate in breast cancer therapeutics

A synergistic approach of adapalene-loaded nanostructured lipid carriers, and vitamin C co-administration for treating acne

Quality by design (QbD)-based development and optimization of a simple, robust RP-HPLC method for the estimation of methotrexate

Triamcinolone acetonide loaded-cationic nano-lipoidal formulation for uveitis: Evidences of improved biopharmaceutical performance and anti-inflammatory activity

Nanolipoidal α-terpineol modulates quorum sensing regulated virulence and biofilm formation in Pseudomonas aeruginosa

Lipid nanocarrier-mediated drug delivery system to enhance the oral bioavailability of rifabutin

Nano-constructed carriers loaded with antioxidant: Boon for cardiovascular system